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Large-Scale Analysis of X Inactivation Variations between Primed and Naïve Human Embryonic Stem Cells
X chromosome inactivation is a mammalian dosage compensation mechanism, where one of two X chromosomes is randomly inactivated in female cells. Previous studies have suggested that primed human embryonic stem cells (hESCs) maintain an eroded state of the X chromosome and do not express XIST, while i...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179337/ https://www.ncbi.nlm.nih.gov/pubmed/35681423 http://dx.doi.org/10.3390/cells11111729 |