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Large-Scale Analysis of X Inactivation Variations between Primed and Naïve Human Embryonic Stem Cells

X chromosome inactivation is a mammalian dosage compensation mechanism, where one of two X chromosomes is randomly inactivated in female cells. Previous studies have suggested that primed human embryonic stem cells (hESCs) maintain an eroded state of the X chromosome and do not express XIST, while i...

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Detalles Bibliográficos
Autores principales: Sarel-Gallily, Roni, Benvenisty, Nissim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179337/
https://www.ncbi.nlm.nih.gov/pubmed/35681423
http://dx.doi.org/10.3390/cells11111729