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Differential Effects of Dietary Macronutrients on the Development of Oncogenic KRAS-Mediated Pancreatic Ductal Adenocarcinoma

SIMPLE SUMMARY: Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal disease and oncogenic KRAS mutations are prevalent in PDAC patients. Oncogenic KRAS is critical for the initiation and development of PDAC; however, it alone is insufficient to drive pancreatic cancer. Oncogenic KRAS is an im...

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Detalles Bibliográficos
Autores principales: Zhu, Liang, Ji, Juntao, Ma, Jianjia, Wang, Dan, Liu, Muyun, Du, James Xianxing, Chen, Rong, Hou, Wei, Abbruzzese, James L., Logsdon, Craig D., Yang, Vincent W., Luo, Yongde, Lu, Weiqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179355/
https://www.ncbi.nlm.nih.gov/pubmed/35681705
http://dx.doi.org/10.3390/cancers14112723