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Cancer-Associated Fibroblasts Confer Gemcitabine Resistance to Pancreatic Cancer Cells through PTEN-Targeting miRNAs in Exosomes

SIMPLE SUMMARY: Previous studies have shown that cancer associated fibroblasts exposed to chemotherapy release exosomes which promote chemoresistance in recipient cells. However, the molecular mechanism responsible for this has not been fully elucidated. In this study, we found that gemcitabine trea...

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Detalles Bibliográficos
Autores principales: Richards, Katherine E., Xiao, Weikun, Hill, Reginald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179363/
https://www.ncbi.nlm.nih.gov/pubmed/35681792
http://dx.doi.org/10.3390/cancers14112812