Validation Study for Non-Invasive Prediction of IDH Mutation Status in Patients with Glioma Using In Vivo (1)H-Magnetic Resonance Spectroscopy and Machine Learning

SIMPLE SUMMARY: The enzyme isocitrate dehydrogenase (IDH) affects glioma cell metabolism in multiple ways. Mutation of IDH is not only indicative of the presence of astrocytoma or oligodendroglioma but it also comes with a better prognosis and constitutes a promising therapeutic target. Therefore, d...

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Detalles Bibliográficos
Autores principales: Bumes, Elisabeth, Fellner, Claudia, Fellner, Franz A., Fleischanderl, Karin, Häckl, Martina, Lenz, Stefan, Linker, Ralf, Mirus, Tim, Oefner, Peter J., Paar, Christian, Proescholdt, Martin Andreas, Riemenschneider, Markus J., Rosengarth, Katharina, Weis, Serge, Wendl, Christina, Wimmer, Sibylle, Hau, Peter, Gronwald, Wolfram, Hutterer, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179368/
https://www.ncbi.nlm.nih.gov/pubmed/35681741
http://dx.doi.org/10.3390/cancers14112762

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179368/
https://www.ncbi.nlm.nih.gov/pubmed/35681741
http://dx.doi.org/10.3390/cancers14112762

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