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Validation Study for Non-Invasive Prediction of IDH Mutation Status in Patients with Glioma Using In Vivo (1)H-Magnetic Resonance Spectroscopy and Machine Learning
SIMPLE SUMMARY: The enzyme isocitrate dehydrogenase (IDH) affects glioma cell metabolism in multiple ways. Mutation of IDH is not only indicative of the presence of astrocytoma or oligodendroglioma but it also comes with a better prognosis and constitutes a promising therapeutic target. Therefore, d...
Autores principales: | Bumes, Elisabeth, Fellner, Claudia, Fellner, Franz A., Fleischanderl, Karin, Häckl, Martina, Lenz, Stefan, Linker, Ralf, Mirus, Tim, Oefner, Peter J., Paar, Christian, Proescholdt, Martin Andreas, Riemenschneider, Markus J., Rosengarth, Katharina, Weis, Serge, Wendl, Christina, Wimmer, Sibylle, Hau, Peter, Gronwald, Wolfram, Hutterer, Markus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179368/ https://www.ncbi.nlm.nih.gov/pubmed/35681741 http://dx.doi.org/10.3390/cancers14112762 |
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