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Functional Peptides from SARS-CoV-2 Binding with Cell Membrane: From Molecular Dynamics Simulations to Cell Demonstration

Herein, we have verified the interaction between the functional peptides from the SARS-CoV-2 and cell membrane, and we further proved that peptides exhibit little membrane disruption. The specific amino acids (Lys, Ile, Glu, Asn, Gln, etc.) with charge or hydrophobic residues play a significant role...

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Detalles Bibliográficos
Autores principales: Hao, Yun, Wu, Rongrong, Wang, Fenghua, Zhang, Liwei, Wang, Zengkai, Song, Xiaolu, Liu, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179371/
https://www.ncbi.nlm.nih.gov/pubmed/35681433
http://dx.doi.org/10.3390/cells11111738