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Survival Benefit of Statin with Anti-Angiogenesis Efficacy in Lung Cancer-Associated Pleural Fluid through FXR Modulation

SIMPLE SUMMARY: Our previous works showed that pleural fluid from lung cancer significantly induced endothelial proliferation, migration, and angiogenesis. Since endothelial metabolism was a key step in angiogenesis, we investigated the role of bile acid signaling and FXR expression in pleural angio...

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Detalles Bibliográficos
Autores principales: Tsai, Chen-Liang, Changchien, Chih-Ying, Chen, Ying, Lai, Chine-Rui, Chen, Tzu-Min, Chang, Hsin-Han, Tsai, Wen-Chiuan, Tsai, Yu-Ling, Tsai, Hao-Chung, Lin, Hung-Yi, Wang, Chieh-Yung, Shen, Ming-Sheng, Lin, Yu-Huei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179389/
https://www.ncbi.nlm.nih.gov/pubmed/35681743
http://dx.doi.org/10.3390/cancers14112765