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Multivariate Risk Analysis of RAS, BRAF and EGFR Mutations Allelic Frequency and Coexistence as Colorectal Cancer Predictive Biomarkers

SIMPLE SUMMARY: The colorectal cancer (CRC) stage and evolution should be described by biomarker profiles. In 60 CRC cases, KRAS, NRAS, BRAF, and EGFR mutations were analyzed by droplet digital PCR (ddPCR). KRAS G12/G13 mutation was present in all patients with variable allelic frequencies. KRAS Q61...

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Detalles Bibliográficos
Autores principales: Ionescu, Adriana, Bilteanu, Liviu, Geicu, Ovidiu Ionut, Iordache, Florin, Stanca, Loredana, Pisoschi, Aurelia Magdalena, Miron, Adrian, Serban, Andreea Iren, Calu, Valentin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179415/
https://www.ncbi.nlm.nih.gov/pubmed/35681771
http://dx.doi.org/10.3390/cancers14112792