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Oncogenic KRAS-Induced Protein Signature in the Tumor Secretome Identifies Laminin-C2 and Pentraxin-3 as Useful Biomarkers for the Early Diagnosis of Pancreatic Cancer

SIMPLE SUMMARY: Pancreatic ductal adenocarcinoma is an aggressive neoplasia that responds poorly to treatments and is frequently recognized at advanced stages. Early diagnosis and the possibility to undergo resective surgery would increase the rate of patient survival and the chance of a definitive...

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Detalles Bibliográficos
Autores principales: Kamal, Mohammad Azhar, Siddiqui, Imran, Belgiovine, Cristina, Barbagallo, Marialuisa, Paleari, Valentina, Pistillo, Daniela, Chiabrando, Chiara, Schiarea, Silvia, Bottazzi, Barbara, Leone, Roberto, Avigni, Roberta, Migliore, Roberta, Spaggiari, Paola, Gavazzi, Francesca, Capretti, Giovanni, Marchesi, Federica, Mantovani, Alberto, Zerbi, Alessandro, Allavena, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179463/
https://www.ncbi.nlm.nih.gov/pubmed/35681634
http://dx.doi.org/10.3390/cancers14112653