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Pitavastatin Is Anti-Leukemic in a Bone Marrow Microenvironment Model of B-Lineage Acute Lymphoblastic Leukemia

SIMPLE SUMMARY: Chemoresistance after chemotherapy is a negative prognostic indicator for B-cell acute lymphoblastic leukemia (ALL), necessitating the search for novel therapies. By growing ALL cells together with bone marrow stromal cells, we developed a chemoresistant ALL model. Using this model,...

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Detalles Bibliográficos
Autores principales: Piktel, Debbie, Nair, Rajesh R., Rellick, Stephanie L., Geldenhuys, Werner J., Martin, Karen H., Craig, Michael D., Gibson, Laura F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179467/
https://www.ncbi.nlm.nih.gov/pubmed/35681662
http://dx.doi.org/10.3390/cancers14112681