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Pitavastatin Is Anti-Leukemic in a Bone Marrow Microenvironment Model of B-Lineage Acute Lymphoblastic Leukemia
SIMPLE SUMMARY: Chemoresistance after chemotherapy is a negative prognostic indicator for B-cell acute lymphoblastic leukemia (ALL), necessitating the search for novel therapies. By growing ALL cells together with bone marrow stromal cells, we developed a chemoresistant ALL model. Using this model,...
Autores principales: | Piktel, Debbie, Nair, Rajesh R., Rellick, Stephanie L., Geldenhuys, Werner J., Martin, Karen H., Craig, Michael D., Gibson, Laura F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179467/ https://www.ncbi.nlm.nih.gov/pubmed/35681662 http://dx.doi.org/10.3390/cancers14112681 |
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