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Antigen-Specific T Cell Immunotherapy Targeting Claudin18.2 in Gastric Cancer

SIMPLE SUMMARY: Claudin18.2 is expressed in the primary and metastatic gastric cancer, making Claudin18.2 a suitable target for antigen-specific T cell immunotherapy. In this study, we first identified 12 Claudin18.2 peptides that had immunogenicity, and found that T cells stimulated by Claudin18.2...

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Detalles Bibliográficos
Autores principales: Xu, Bo, Chen, Fangjun, Zhang, Xin, Wang, Zhongda, Che, Keying, Wu, Nandie, Yu, Lixia, Fan, Xiangshan, Liu, Baorui, Wei, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179507/
https://www.ncbi.nlm.nih.gov/pubmed/35681738
http://dx.doi.org/10.3390/cancers14112758