Reducing PDK1/Akt Activity: An Effective Therapeutic Target in the Treatment of Alzheimer’s Disease

Alzheimer’s disease (AD) is a common age-related neurodegenerative disease that leads to memory loss and cognitive function damage due to intracerebral neurofibrillary tangles (NFTs) and amyloid-β (Aβ) protein deposition. The phosphoinositide-dependent protein kinase (PDK1)/protein kinase B (Akt) si...

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Detalles Bibliográficos
Autores principales: Yang, Shaobin, Du, Yaqin, Zhao, Xiaoqian, Wu, Chendong, Yu, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179555/
https://www.ncbi.nlm.nih.gov/pubmed/35681431
http://dx.doi.org/10.3390/cells11111735

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179555/
https://www.ncbi.nlm.nih.gov/pubmed/35681431
http://dx.doi.org/10.3390/cells11111735

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