Extracellular Vesicle-Based Method for Detecting MYCN Amplification Status of Pediatric Neuroblastoma

SIMPLE SUMMARY: MYCN gene amplification, the strongest prognostic marker of aggressive neuroblastoma, is detected on invasive biopsy tissues. This study aimed to establish a less invasive method to detect MYCN status based on MYCN mRNA contents in large extracellular vesicles or microvesicles. MYCN...

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Detalles Bibliográficos
Autores principales: Panachan, Jirawan, Rojsirikulchai, Napat, Pongsakul, Nutkridta, Khowawisetsut, Ladawan, Pongphitcha, Pongpak, Siriboonpiputtana, Teerapong, Chareonsirisuthigul, Takol, Phornsarayuth, Pitichai, Klinkulab, Nisakorn, Jinawath, Natini, Chiangjong, Wararat, Anurathapan, Usanarat, Pattanapanyasat, Kovit, Hongeng, Suradej, Chutipongtanate, Somchai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179557/
https://www.ncbi.nlm.nih.gov/pubmed/35681607
http://dx.doi.org/10.3390/cancers14112627

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179557/
https://www.ncbi.nlm.nih.gov/pubmed/35681607
http://dx.doi.org/10.3390/cancers14112627

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