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The Outside-In Journey of Tissue Transglutaminase in Cancer
Tissue transglutaminase (TG2) is a member of the transglutaminase family that catalyzes Ca(2+)-dependent protein crosslinks and hydrolyzes guanosine 5′-triphosphate (GTP). The conformation and functions of TG2 are regulated by Ca(2+) and GTP levels; the TG2 enzymatically active open conformation is...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179582/ https://www.ncbi.nlm.nih.gov/pubmed/35681474 http://dx.doi.org/10.3390/cells11111779 |