Hypoxia Selectively Increases a SMAD3 Signaling Axis to Promote Cancer Cell Invasion

SIMPLE SUMMARY: While 90% of cancer patient deaths are caused by cancer dissemination through metastasis, no current therapy selectively targets this process due to the lack of selective inhibitors. Various intratumoral factors are known to promote metastasis, notably low oxygen concentration, calle...

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Detalles Bibliográficos
Autores principales: Brochu-Gaudreau, Karine, Charbonneau, Martine, Harper, Kelly, Dubois, Claire M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179584/
https://www.ncbi.nlm.nih.gov/pubmed/35681731
http://dx.doi.org/10.3390/cancers14112751

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179584/
https://www.ncbi.nlm.nih.gov/pubmed/35681731
http://dx.doi.org/10.3390/cancers14112751

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