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Hypoxia Selectively Increases a SMAD3 Signaling Axis to Promote Cancer Cell Invasion
SIMPLE SUMMARY: While 90% of cancer patient deaths are caused by cancer dissemination through metastasis, no current therapy selectively targets this process due to the lack of selective inhibitors. Various intratumoral factors are known to promote metastasis, notably low oxygen concentration, calle...
Autores principales: | Brochu-Gaudreau, Karine, Charbonneau, Martine, Harper, Kelly, Dubois, Claire M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179584/ https://www.ncbi.nlm.nih.gov/pubmed/35681731 http://dx.doi.org/10.3390/cancers14112751 |
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