Tropomyosin-Related Kinase Fusions in Gastrointestinal Stromal Tumors

SIMPLE SUMMARY: The canonical mutations in gastrointestinal stromal tumors (GISTs) are typically activating mutations in KIT and platelet-derived growth factor receptor alpha (PDGFRA). Imatinib, the treatment of choice for GISTs, shows a lower response in KIT/PDGFRA wild-type GISTs. Neurotrophic tyr...

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Detalles Bibliográficos
Autores principales: Lee, Ji Hyun, Shin, Su-Jin, Choe, Eun-Ah, Kim, Jungyoun, Hyung, Woo Jin, Kim, Hyo Song, Jung, Minkyu, Beom, Seung-Hoon, Kim, Tae Il, Ahn, Joong Bae, Chung, Hyun Cheol, Shin, Sang Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179593/
https://www.ncbi.nlm.nih.gov/pubmed/35681640
http://dx.doi.org/10.3390/cancers14112659

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179593/
https://www.ncbi.nlm.nih.gov/pubmed/35681640
http://dx.doi.org/10.3390/cancers14112659

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