Targeting MUC1-C Suppresses Chronic Activation of Cytosolic Nucleotide Receptors and STING in Triple-Negative Breast Cancer

SIMPLE SUMMARY: Triple-negative breast cancers (TNBCs) are recalcitrant tumors with limited therapeutic options. Cytotoxic agents, including platinum-based drugs, are a standard of care for advanced TNBCs. Olaparib is also used for the treatment of germline BRCA mutant TNBC tumors in the adjuvant an...

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Detalles Bibliográficos
Autores principales: Yamashita, Nami, Fushimi, Atsushi, Morimoto, Yoshihiro, Bhattacharya, Atrayee, Hagiwara, Masayuki, Yamamoto, Masaaki, Hata, Tsuyoshi, Shapiro, Geoffrey I., Long, Mark D., Liu, Song, Kufe, Donald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179855/
https://www.ncbi.nlm.nih.gov/pubmed/35681561
http://dx.doi.org/10.3390/cancers14112580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179855/
https://www.ncbi.nlm.nih.gov/pubmed/35681561
http://dx.doi.org/10.3390/cancers14112580

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