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The CXCL12/CXCR4/ACKR3 Signaling Axis Regulates PKM2 and Glycolysis
In response to CXCL12, CXCR4 and ACKR3 both recruit β-arrestin 2, regulating the assembly of interacting proteins that drive signaling and contribute to the functions of both receptors in cancer and multiple other diseases. A prior proteomics study revealed that β-arrestin 2 scaffolds pyruvate kinas...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179862/ https://www.ncbi.nlm.nih.gov/pubmed/35681470 http://dx.doi.org/10.3390/cells11111775 |