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Fusogenic Hybrid Extracellular Vesicles with PD-1 Membrane Proteins for the Cytosolic Delivery of Cargos

SIMPLE SUMMARY: We developed a method using cell-derived lipid membrane capsules—called extracellular vesicles (EVs)—to deliver a model cargo into cytosol. These EVs were fused with liposomes (to form hybrid EVs) because cargo molecules can be more easily encapsulated within liposomes than EVs. EVs...

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Detalles Bibliográficos
Autores principales: Ishikawa, Raga, Yoshida, Shosuke, Sawada, Shin-ichi, Sasaki, Yoshihiro, Akiyoshi, Kazunari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179877/
https://www.ncbi.nlm.nih.gov/pubmed/35681615
http://dx.doi.org/10.3390/cancers14112635