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Vitronectin and Its Interaction with PAI-1 Suggests a Functional Link to Vascular Changes in AMD Pathobiology

The pathogenesis of age-related macular degeneration (AMD), a frequent disorder of the central retina, is incompletely understood. Genome-wide association studies (GWAS) suggest a strong contribution of genomic variation in AMD susceptibility. Nevertheless, little is known about biological mechanism...

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Detalles Bibliográficos
Autores principales: Biasella, Fabiola, Strunz, Tobias, Kiel, Christina, Weber, Bernhard H. F., Friedrich, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179922/
https://www.ncbi.nlm.nih.gov/pubmed/35681461
http://dx.doi.org/10.3390/cells11111766