Cargando…
Vitronectin and Its Interaction with PAI-1 Suggests a Functional Link to Vascular Changes in AMD Pathobiology
The pathogenesis of age-related macular degeneration (AMD), a frequent disorder of the central retina, is incompletely understood. Genome-wide association studies (GWAS) suggest a strong contribution of genomic variation in AMD susceptibility. Nevertheless, little is known about biological mechanism...
Autores principales: | Biasella, Fabiola, Strunz, Tobias, Kiel, Christina, Weber, Bernhard H. F., Friedrich, Ulrike |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179922/ https://www.ncbi.nlm.nih.gov/pubmed/35681461 http://dx.doi.org/10.3390/cells11111766 |
Ejemplares similares
-
Altered Protein Function Caused by AMD-associated Variant rs704 Links Vitronectin to Disease Pathology
por: Biasella, Fabiola, et al.
Publicado: (2020) -
Pleiotropic Locus 15q24.1 Reveals a Gender-Specific Association with Neovascular but Not Atrophic Age-Related Macular Degeneration (AMD)
por: Kiel, Christina, et al.
Publicado: (2020) -
NLRP3 Inflammasome and Pathobiology in AMD
por: Celkova, Lucia, et al.
Publicado: (2015) -
Perspective on AMD Pathobiology: A Bioenergetic Crisis in the RPE
por: Fisher, Cody R., et al.
Publicado: (2018) -
The Plasminogen Activator Inhibitor PAI-1 Controls in Vivo Tumor Vascularization by Interaction with Proteases, Not Vitronectin: Implications for Antiangiogenic Strategies
por: Bajou, Khalid, et al.
Publicado: (2001)