Inhibition of HDAC and Signal Transduction Pathways Induces Tight Junctions and Promotes Differentiation in p63-Positive Salivary Duct Adenocarcinoma

SIMPLE SUMMARY: The p53 family p63 gene is essential for the proliferation and differentiation of various epithelial cells, and it is overexpressed in some salivary gland neoplasia. Histone deacetylases (HDACs) are thought to play a crucial role in carcinogenesis, and HDAC inhibitors downregulate p6...

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Detalles Bibliográficos
Autores principales: Nakano, Masaya, Ohwada, Kizuku, Shindo, Yuma, Konno, Takumi, Kohno, Takayuki, Kikuchi, Shin, Tsujiwaki, Mitsuhiro, Ishii, Daichi, Nishida, Soshi, Kakuki, Takuya, Obata, Kazufumi, Miyata, Ryo, Kurose, Makoto, Kondoh, Atsushi, Takano, Kenichi, Kojima, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179926/
https://www.ncbi.nlm.nih.gov/pubmed/35681564
http://dx.doi.org/10.3390/cancers14112584

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179926/
https://www.ncbi.nlm.nih.gov/pubmed/35681564
http://dx.doi.org/10.3390/cancers14112584

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