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p66Shc in Cardiovascular Pathology

p66Shc is a widely expressed protein that governs a variety of cardiovascular pathologies by generating, and exacerbating, pro-apoptotic ROS signals. Here, we review p66Shc’s connections to reactive oxygen species, expression, localization, and discuss p66Shc signaling and mitochondrial functions. E...

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Detalles Bibliográficos
Autores principales: Haslem, Landon, Hays, Jennifer M., Hays, Franklin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180016/
https://www.ncbi.nlm.nih.gov/pubmed/35681549
http://dx.doi.org/10.3390/cells11111855