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Mass Spectrometry-Based Disulfide Mapping of Lysyl Oxidase-like 2

Lysyl oxidase-like 2 (LOXL2) catalyzes the oxidative deamination of peptidyl lysines and hydroxylysines to promote extracellular matrix remodeling. Aberrant activity of LOXL2 has been associated with organ fibrosis and tumor metastasis. The lysine tyrosylquinone (LTQ) cofactor is derived from Lys653...

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Detalles Bibliográficos
Autores principales: Meier, Alex A., Go, Eden P., Moon, Hee-Jung, Desaire, Heather, Mure, Minae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180022/
https://www.ncbi.nlm.nih.gov/pubmed/35682561
http://dx.doi.org/10.3390/ijms23115879