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Mass Spectrometry-Based Disulfide Mapping of Lysyl Oxidase-like 2
Lysyl oxidase-like 2 (LOXL2) catalyzes the oxidative deamination of peptidyl lysines and hydroxylysines to promote extracellular matrix remodeling. Aberrant activity of LOXL2 has been associated with organ fibrosis and tumor metastasis. The lysine tyrosylquinone (LTQ) cofactor is derived from Lys653...
Autores principales: | Meier, Alex A., Go, Eden P., Moon, Hee-Jung, Desaire, Heather, Mure, Minae |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180022/ https://www.ncbi.nlm.nih.gov/pubmed/35682561 http://dx.doi.org/10.3390/ijms23115879 |
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