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Pathobiology and Therapeutic Relevance of GSK-3 in Chronic Hematological Malignancies

Glycogen synthase kinase-3 (GSK-3) is an evolutionarily conserved, ubiquitously expressed, multifunctional serine/threonine protein kinase involved in the regulation of a variety of physiological processes. GSK-3 comprises two isoforms (α and β) which were originally discovered in 1980 as enzymes in...

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Detalles Bibliográficos
Autores principales: Martelli, Alberto M., Paganelli, Francesca, Evangelisti, Camilla, Chiarini, Francesca, McCubrey, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180032/
https://www.ncbi.nlm.nih.gov/pubmed/35681507
http://dx.doi.org/10.3390/cells11111812