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Pathobiology and Therapeutic Relevance of GSK-3 in Chronic Hematological Malignancies
Glycogen synthase kinase-3 (GSK-3) is an evolutionarily conserved, ubiquitously expressed, multifunctional serine/threonine protein kinase involved in the regulation of a variety of physiological processes. GSK-3 comprises two isoforms (α and β) which were originally discovered in 1980 as enzymes in...
Autores principales: | Martelli, Alberto M., Paganelli, Francesca, Evangelisti, Camilla, Chiarini, Francesca, McCubrey, James A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180032/ https://www.ncbi.nlm.nih.gov/pubmed/35681507 http://dx.doi.org/10.3390/cells11111812 |
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