The Transcription Factor EB (TFEB) Sensitizes the Heart to Chronic Pressure Overload

The transcription factor EB (TFEB) promotes protein degradation by the autophagy and lysosomal pathway (ALP) and overexpression of TFEB was suggested for the treatment of ALP-related diseases that often affect the heart. However, TFEB-mediated ALP induction may perturb cardiac stress response. We us...

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Detalles Bibliográficos
Autores principales: Wundersitz, Sebastian, Pablo Tortola, Cristina, Schmidt, Sibylle, Oliveira Vidal, Ramon, Kny, Melanie, Hahn, Alexander, Zanders, Lukas, Katus, Hugo A., Sauer, Sascha, Butter, Christian, Luft, Friedrich C., Müller, Oliver J., Fielitz, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180101/
https://www.ncbi.nlm.nih.gov/pubmed/35682624
http://dx.doi.org/10.3390/ijms23115943

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180101/
https://www.ncbi.nlm.nih.gov/pubmed/35682624
http://dx.doi.org/10.3390/ijms23115943

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