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The Transcription Factor EB (TFEB) Sensitizes the Heart to Chronic Pressure Overload
The transcription factor EB (TFEB) promotes protein degradation by the autophagy and lysosomal pathway (ALP) and overexpression of TFEB was suggested for the treatment of ALP-related diseases that often affect the heart. However, TFEB-mediated ALP induction may perturb cardiac stress response. We us...
Autores principales: | Wundersitz, Sebastian, Pablo Tortola, Cristina, Schmidt, Sibylle, Oliveira Vidal, Ramon, Kny, Melanie, Hahn, Alexander, Zanders, Lukas, Katus, Hugo A., Sauer, Sascha, Butter, Christian, Luft, Friedrich C., Müller, Oliver J., Fielitz, Jens |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180101/ https://www.ncbi.nlm.nih.gov/pubmed/35682624 http://dx.doi.org/10.3390/ijms23115943 |
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