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Claudin-17 Deficiency in Mice Results in Kidney Injury Due to Electrolyte Imbalance and Oxidative Stress

The multi-gene claudin (CLDN) family of tight junction proteins have isoform-specific roles in blood–tissue barrier regulation. CLDN17, a putative anion pore-forming CLDN based on its structural characterization, is assumed to regulate anion balance across the blood-tissue barriers. However, our kno...

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Detalles Bibliográficos
Autores principales: Adil, Mir S., Parvathagiri, Varun, Verma, Arti, Liu, Fang, Rudraraju, Madhuri, Narayanan, S. Priya, Somanath, Payaningal R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180152/
https://www.ncbi.nlm.nih.gov/pubmed/35681477
http://dx.doi.org/10.3390/cells11111782