SPARC Induces E-Cadherin Repression and Enhances Cell Migration through Integrin αvβ3 and the Transcription Factor ZEB1 in Prostate Cancer Cells

Secreted protein acidic and rich in cysteine (SPARC), or osteonectin, is a matricellular protein that modulates interactions between cells and their microenvironment. SPARC is expressed during extracellular matrix remodeling and is abundant in bone marrow and high-grade prostate cancer (PCa). In PCa...

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Detalles Bibliográficos
Autores principales: López-Moncada, Fernanda, Torres, María José, Lavanderos, Boris, Cerda, Oscar, Castellón, Enrique A., Contreras, Héctor R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180154/
https://www.ncbi.nlm.nih.gov/pubmed/35682554
http://dx.doi.org/10.3390/ijms23115874

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180154/
https://www.ncbi.nlm.nih.gov/pubmed/35682554
http://dx.doi.org/10.3390/ijms23115874

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