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SPARC Induces E-Cadherin Repression and Enhances Cell Migration through Integrin αvβ3 and the Transcription Factor ZEB1 in Prostate Cancer Cells
Secreted protein acidic and rich in cysteine (SPARC), or osteonectin, is a matricellular protein that modulates interactions between cells and their microenvironment. SPARC is expressed during extracellular matrix remodeling and is abundant in bone marrow and high-grade prostate cancer (PCa). In PCa...
Autores principales: | López-Moncada, Fernanda, Torres, María José, Lavanderos, Boris, Cerda, Oscar, Castellón, Enrique A., Contreras, Héctor R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180154/ https://www.ncbi.nlm.nih.gov/pubmed/35682554 http://dx.doi.org/10.3390/ijms23115874 |
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