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Amentoflavone Promotes Cellular Uptake and Degradation of Amyloid-Beta in Neuronal Cells

Deposition of fibrillar forms of amyloid β-protein (Aβ) is commonly found in patients with Alzheimer’s disease (AD) associated with cognitive decline. Impaired clearance of Aβ species is thought to be a major cause of late-onset sporadic AD. Aβ secreted into the extracellular milieu can be cleared f...

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Detalles Bibliográficos
Autores principales: Han, Byung Hee, Cofell, Brooke, Everhart, Emily, Humpal, Courtney, Kang, Sam-Sik, Lee, Sang Kook, Kim-Han, Jeong Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180170/
https://www.ncbi.nlm.nih.gov/pubmed/35682567
http://dx.doi.org/10.3390/ijms23115885