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Autophagy Protects against Eosinophil Cytolysis and Release of DNA

The presence of eosinophils in the airway is associated with asthma severity and risk of exacerbations. Eosinophils deposit their damaging products in airway tissue, likely by degranulation and cytolysis. We previously showed that priming blood eosinophils with IL3 strongly increased their cytolysis...

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Detalles Bibliográficos
Autores principales: Esnault, Stephane, Fichtinger, Paul S., Barretto, Karina T., Fogerty, Frances J., Bernau, Ksenija, Mosher, Deane F., Mathur, Sameer K., Sandbo, Nathan, Jarjour, Nizar N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180302/
https://www.ncbi.nlm.nih.gov/pubmed/35681515
http://dx.doi.org/10.3390/cells11111821