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Peroxisome Metabolism Contributes to PIEZO2-Mediated Mechanical Allodynia

Mutations in the peroxisomal half-transporter ABCD1 cause X-linked adrenoleukodystrophy, resulting in elevated very long-chain fatty acids (VLCFA), progressive neurodegeneration and an associated pain syndrome that is poorly understood. In the nervous system of mice, we found ABCD1 expression to be...

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Detalles Bibliográficos
Autores principales: Gong, Yi, Laheji, Fiza, Berenson, Anna, Qian, April, Park, Sang-O, Kok, Rene, Selig, Martin, Hahn, Ryan, Sadjadi, Reza, Kemp, Stephan, Eichler, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180358/
https://www.ncbi.nlm.nih.gov/pubmed/35681537
http://dx.doi.org/10.3390/cells11111842