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Structural Aspects of E. coli Type II Asparaginase in Complex with Its Secondary Product L-Glutamate
Bacterial L-asparaginases are amidohydrolases (EC 3.5.1.1) capable of deaminating L-asparagine and, with reduced efficiency, L-glutamine. Interest in the study of L-asparaginases is driven by their use as biodrugs for the treatment of acute lymphoblastic leukemia. Here, we report for the first time...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180372/ https://www.ncbi.nlm.nih.gov/pubmed/35682622 http://dx.doi.org/10.3390/ijms23115942 |