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Understanding the Underlying Molecular Mechanisms of Meiotic Arrest during In Vitro Spermatogenesis in Rat Prepubertal Testicular Tissue

In vitro spermatogenesis appears to be a promising approach to restore the fertility of childhood cancer survivors. The rat model has proven to be challenging, since germ cell maturation is arrested in organotypic cultures. Here, we report that, despite a meiotic entry, abnormal synaptonemal complex...

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Detalles Bibliográficos
Autores principales: Saulnier, Justine, Chalmel, Frédéric, Delessard, Marion, Moutard, Laura, Pereira, Tony, Fraissinet, François, Dumont, Ludovic, Rives-Feraille, Aurélie, Rondanino, Christine, Rives, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180380/
https://www.ncbi.nlm.nih.gov/pubmed/35682573
http://dx.doi.org/10.3390/ijms23115893