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Mitochondrial Dysfunction in Spinocerebellar Ataxia Type 3 Is Linked to VDAC1 Deubiquitination

Dysfunctional mitochondria are linked to several neurodegenerative diseases. Metabolic defects, a symptom which can result from dysfunctional mitochondria, are also present in spinocerebellar ataxia type 3 (SCA3), also known as Machado–Joseph disease, the most frequent, dominantly inherited neurodeg...

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Detalles Bibliográficos
Autores principales: Harmuth, Tina, Weber, Jonasz J., Zimmer, Anna J., Sowa, Anna S., Schmidt, Jana, Fitzgerald, Julia C., Schöls, Ludger, Riess, Olaf, Hübener-Schmid, Jeannette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180688/
https://www.ncbi.nlm.nih.gov/pubmed/35682609
http://dx.doi.org/10.3390/ijms23115933