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Single Cell/Nucleus Transcriptomics Comparison in Zebrafish and Humans Reveals Common and Distinct Molecular Responses to Alzheimer’s Disease

Neurogenesis is significantly reduced in Alzheimer’s disease (AD) and is a potential therapeutic target. Contrary to humans, a zebrafish can regenerate its diseased brain, and thus is ideal for studying neurogenesis. To compare the AD-related molecular pathways between humans and zebrafish, we compa...

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Detalles Bibliográficos
Autores principales: Cosacak, Mehmet Ilyas, Bhattarai, Prabesh, De Jager, Philip L., Menon, Vilas, Tosto, Giuseppe, Kizil, Caghan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180693/
https://www.ncbi.nlm.nih.gov/pubmed/35681503
http://dx.doi.org/10.3390/cells11111807