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G-Protein-Coupled Estrogen Receptor Expression in Rat Uterine Artery Is Increased by Pregnancy and Induces Dilation in a Ca(2+) and ERK1/2 Dependent Manner

Increasing levels of estrogens across gestation are partly responsible for the physiological adaptations of the maternal vasculature to pregnancy. The G protein-coupled estrogen receptor (GPER) mediates acute vasorelaxing effects in the uterine vasculature, which may contribute to the regulation of...

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Detalles Bibliográficos
Autores principales: Tropea, Teresa, Rigiracciolo, Damiano, Esposito, Milena, Maggiolini, Marcello, Mandalà, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180712/
https://www.ncbi.nlm.nih.gov/pubmed/35682675
http://dx.doi.org/10.3390/ijms23115996