Immune Checkpoint Proteins, Metabolism and Adhesion Molecules: Overlooked Determinants of CAR T-Cell Migration?

Adoptive transfer of T cells genetically engineered to express chimeric antigen receptors (CAR) has demonstrated striking efficacy for the treatment of several hematological malignancies, including B-cell lymphoma, leukemia, and multiple myeloma. However, many patients still do not respond to this t...

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Detalles Bibliográficos
Autores principales: Simula, Luca, Ollivier, Emma, Icard, Philippe, Donnadieu, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180731/
https://www.ncbi.nlm.nih.gov/pubmed/35681548
http://dx.doi.org/10.3390/cells11111854

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180731/
https://www.ncbi.nlm.nih.gov/pubmed/35681548
http://dx.doi.org/10.3390/cells11111854

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