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Interaction between Bacteria and the Immune System for Cancer Immunotherapy: The α-GalCer Alliance

Non-conventional T cells, such as γδ T and invariant natural killer T (iNKT) cells, are emerging players in fighting cancer. Alpha-galactosylceramide (α-GalCer) is used as an exogenous ligand to activate iNKT cells. Human cells don’t have a direct pathway producing α-GalCer, which, however, can be p...

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Detalles Bibliográficos
Autores principales: Ustjanzew, Arsenij, Sencio, Valentin, Trottein, François, Faber, Jörg, Sandhoff, Roger, Paret, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180740/
https://www.ncbi.nlm.nih.gov/pubmed/35682578
http://dx.doi.org/10.3390/ijms23115896