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LSD1 Inhibition Enhances the Immunogenicity of Mesenchymal Stromal Cells by Eliciting a dsRNA Stress Response

Mesenchymal stromal cells (MSCs) are commonly known for their immune-suppressive abilities. However, our group provided evidence that it is possible to convert MSCs into potent antigen presenting cells (APCs) using either genetic engineering or pharmacological means. Given the capacity of UM171a to...

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Detalles Bibliográficos
Autores principales: Mardani, Fatemeh, Saad, Wael, El-Hachem, Nehme, Bikorimana, Jean-Pierre, Kurdi, Mazen, Shammaa, Riam, Talbot, Sebastien, Rafei, Moutih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180800/
https://www.ncbi.nlm.nih.gov/pubmed/35681511
http://dx.doi.org/10.3390/cells11111816