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LSD1 Inhibition Enhances the Immunogenicity of Mesenchymal Stromal Cells by Eliciting a dsRNA Stress Response
Mesenchymal stromal cells (MSCs) are commonly known for their immune-suppressive abilities. However, our group provided evidence that it is possible to convert MSCs into potent antigen presenting cells (APCs) using either genetic engineering or pharmacological means. Given the capacity of UM171a to...
Autores principales: | Mardani, Fatemeh, Saad, Wael, El-Hachem, Nehme, Bikorimana, Jean-Pierre, Kurdi, Mazen, Shammaa, Riam, Talbot, Sebastien, Rafei, Moutih |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180800/ https://www.ncbi.nlm.nih.gov/pubmed/35681511 http://dx.doi.org/10.3390/cells11111816 |
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