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Endolysosome Iron Chelation Inhibits HIV-1 Protein-Induced Endolysosome De-Acidification-Induced Increases in Mitochondrial Fragmentation, Mitophagy, and Cell Death

People with human immunodeficiency virus-1 (PLWH) experience high rates of HIV-1-associated neurocognitive disorders (HANDs); clinical symptoms range from being asymptomatic to experiencing HIV-associated dementia. Antiretroviral therapies have effectively prolonged the life expectancy related to PL...

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Detalles Bibliográficos
Autores principales: Halcrow, Peter W., Kumar, Nirmal, Quansah, Darius N. K., Baral, Aparajita, Liang, Braelyn, Geiger, Jonathan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180803/
https://www.ncbi.nlm.nih.gov/pubmed/35681506
http://dx.doi.org/10.3390/cells11111811