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Prediction of ACE-I Inhibitory Peptides Derived from Chickpea (Cicer arietinum L.): In Silico Assessments Using Simulated Enzymatic Hydrolysis, Molecular Docking and ADMET Evaluation

Chickpea (Cicer arietinum L.) peptides have shown in vitro potential to inhibit the angiotensin I-converting enzyme (ACE-I). However, the potential molecular interactions between chickpea peptides (CP) and ACE-I as well as their ADMET (absorption/distribution/metabolism/excretion/toxicity) character...

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Detalles Bibliográficos
Autores principales: Arámburo-Gálvez, Jesús Gilberto, Arvizu-Flores, Aldo Alejandro, Cárdenas-Torres, Feliznando Isidro, Cabrera-Chávez, Francisco, Ramírez-Torres, Giovanni I., Flores-Mendoza, Lilian Karem, Gastelum-Acosta, Pedro Erick, Figueroa-Salcido, Oscar Gerardo, Ontiveros, Noé
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180818/
https://www.ncbi.nlm.nih.gov/pubmed/35681326
http://dx.doi.org/10.3390/foods11111576