Quantification of Low Amounts of Zoledronic Acid by HPLC-ESI-MS Analysis: Method Development and Validation

Zoledronic acid (ZA) is used in the treatment of various bone pathologies, but it forms complexes with calcium ions present in body fluids, decreasing ZA bioavailability. Thereby, the study first describes the identification of ZA-calcium complexes that form in calcium-rich environments, in order to...

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Detalles Bibliográficos
Autores principales: Petrovici, Anca-Roxana, Silion, Mihaela, Simionescu, Natalia, Kallala, Rami, Pinteala, Mariana, Maier, Stelian S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180824/
https://www.ncbi.nlm.nih.gov/pubmed/35682618
http://dx.doi.org/10.3390/ijms23115944

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180824/
https://www.ncbi.nlm.nih.gov/pubmed/35682618
http://dx.doi.org/10.3390/ijms23115944

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