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Restructuring of Lamina-Associated Domains in Senescence and Cancer

Induction of cellular senescence or cancer is associated with a reshaping of the nuclear envelope and a broad reorganization of heterochromatin. At the periphery of mammalian nuclei, heterochromatin is stabilized at the nuclear lamina via lamina-associated domains (LADs). Alterations in the composit...

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Detalles Bibliográficos
Autores principales: Bellanger, Aurélie, Madsen-Østerbye, Julia, Galigniana, Natalia M., Collas, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180887/
https://www.ncbi.nlm.nih.gov/pubmed/35681541
http://dx.doi.org/10.3390/cells11111846